Hepatitis C virus (HCV) infection is one of the leading causes of end-stage liver disease and the main indication for liver transplantation (LT) in most countries.All patients who undergo LT with detectable serum HCV RNA experience graft reinfection progressing to cirrhosis within five years in 20% to 30% of them.Obtaining a sustained virological r

Developmental abnormalities of airways may impact susceptibility to asthma in later life.We used a maternal hypoxia-induced mouse model of intrauterine growth restriction (IUGR) to examine changes in mechanical properties of the airway wall.Pregnant BALB/c mice were housed under hypoxic conditions (10.5% O2) from gestational day (GD) 11 to GD 17.5

Although Stegosaurus is one of the most iconic dinosaurs, well-preserved fossils are rare and as a consequence there is still much that remains unknown about the taxon.A new, exceptionally complete individual affords the opportunity to describe the anatomy of Stegosaurus in detail for the first time in over a century, and enables additional compari

During development of biological organisms, multiple complex structures are formed.In domeless quartz nails many instances, these structures need to exhibit a high degree of order to be functional, although many of their constituents are intrinsically stochastic.Hence, it has been suggested that biological robustness ultimately must rely on complex